Supplementary Assay Reagents

764 Entries on 64 Pages
(+-)-Bay K8644

(+-)-Bay K8644

1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl) phenyl]-3-pyridinecarboxylic acid, methyl ester

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PK-CA577-1682-5 $ 289.00
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(+)-N-3-benzylnirvanol

(+)-N-3-benzylnirvanol

Potent and selective inhibitor of CYP2C19.

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2 Variants
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(±)-Gossypol

An anti-cancer agent and inhibitor of LDH and aldose reductase.

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2 Variants
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10X Red Blood Cell Lysis Buffer

10X Red Blood Cell Lysis Buffer

Buffer for efficient removal of RBCs from whole blood, tissues or tumor cells.

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PK-CA577-5831 $ 102.00
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1400W (dihydrochloride)

A slow, tight binding and highly selective, cell-permeable inhibitor of iNOS.

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2 Variants
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17-AAG

A semi-synthetic derivative of Geldanamycin that displays greater stability and lower in vivo toxicity compared to Geldanamycin. Also inhibits Akt activation and HER2 expression in tumor cells.

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2 Variants
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2-Deoxy-D-Glucose

A glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism.

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2 Variants
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2-Methoxyestradiol

Potent inhibitor of endothelial cell proliferation and angiogenesis.

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2 Variants
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2-Methyl-5-hydroxytryptamine hydrochloride

2-Methyl-5-hydroxytryptamine hydrochloride

A 5-HT3 agonist and potent 5-HT6 ligand that has been used as one of the components of the chemical cocktails used for reprogramming of mouse somatic cells toward pluripotent cells in the absence of Oct4.

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2 Variants
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2′-Deoxy-5-fluorocytidine

A DNA methyltransferase (DNMT) inhibitor that acts as a tumor-selective prodrug of the potent thymidylate synthase inhibitor 5-fluoro-2′-dUMP (FdUMP).

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2 Variants
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3-Bromo-7-nitroindazole

A more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS.

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2 Variants
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3-Bromopyruvic Acid

A hexokinase inhibitor that has been shown to abolish ATP production and cause severe depletion of cellular ATP. It also displays potent cytotoxic activity against cancer cells with mitochondrial respiratory defects and cells in hypoxic environment.

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2 Variants
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