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Cardiac regeneration: from cell models to therapeutic strategies

This eBook brings together research insights and practical guidance to help you explore cardiac regeneration from disease modeling through to emerging therapeutic strategies.

Cardiovascular diseases can cause irreversible tissue damage, yet the heart has a limited capacity to regenerate. For researchers, the challenge is not only to develop new strategies for cardiac repair, but also to select human-relevant models and technologies that can generate meaningful, translational insights.

What you'll learn:

  • How 3D cardiac spheroids compare with traditional 2D cultures
  • How to perform and analyze an endothelial tube formation assay for in vitro angiogenesis studies
  • Why primary human cardiovascular cells are relevant for human cardiac models
  • Which design criteria, biomaterials, and fabrication methods are being explored for cardiac patches
  • The advances, limitations, and prospects of mesenchymal and induced pluripotent stem cells for cardiac repair
  • How hydrogel scaffolds and natural extracellular matrix components are being investigated for cardiac regeneration

This eBook was made in collaboration with RegMedNet.

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