PDOs or ex vivo tumor tissue cultures?

Patient-derived organoids (PDOs) and ex vivo tumor slice cultures both help researchers study patient tumor biology, but each preserves different aspects of the disease and serves different experimental needs.

Tumor slice cultures retain much of the native tissue architecture and tumor microenvironment while enabling rapid, short-term studies. PDOs, on the other hand, offer the scalability, expansion potential, and experimental flexibility needed for longer-term studies, repeated testing, and larger drug screens

Join us for our upcoming webinar on Fierce Biotech where we’ll compare the strengths and limitations of both approaches and explore how to select the most appropriate model for different translational research questions.

We’ll also share practical guidance for establishing these models and how our cancer culture solutions can support advanced PDO and tumor tissue culture workflows.

What you’ll learn:

• How PDOs and tumor slice cultures differ in tumor microenvironment preservation, scalability, reproducibility, and experimental timescale
• Where each model offers advantages for drug screening, immunotherapy research, and other translational applications
• Key practical considerations when establishing and maintaining PDO and tumor tissue culture workflows
• How tumor slice cultures and PDOs can be used as complementary models to generate insights from the same patient material

Join our webinar:
PDOs or ex vivo tumor tissue cultures? 

Tuesday, September 29th, 2026

5pm CEST / 11AM EST

This webinar is free and open to the public.
Can’t attend live? No problem. The webinar will also be available to watch on demand after the event.

Alexander Trampe, Ph.D
Cancer Specialist & Project Manager at PromoCell

Alexander Trampe is Project Manager of PromoCell’s Cancer Media Toolbox with nearly 18 years of experience supporting researchers. His expertise centers on cancer cell culture including tumorspheres and more advanced 3D cancer models. He holds a Ph.D. in cell biology from the University of Lübeck and a degree in biochemistry from the University of Bielefeld.