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What proportion of MSCs can be differentiated into neuronal lineages?

When human mesenchymal stem cells (hMSC) are differentiated using PromoCell Mesenchymal Stem Cell Neurogenic Differentiation Medium (C‑28015):
  • Approximately 90–100% of the cells adopt a neuronal‑like morphology.
  • About 60–80% of the differentiated cells are positive for Nissl bodies, as confirmed by Nissl staining.

These results indicate a high differentiation efficiency at the morphological level, with a substantial proportion of cells also showing neuronal cytological features.

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