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Human Uterine Microvascular Endothelial Cells (HUtMEC)
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Primary Human Uterine Microvascular Endothelial Cells isolated from the myometrium from single donors. Donors not pre-treated with hormones.

Unit 500,000 cells
Cat.No.
C-12295
Currently In stock

Primary Human Uterine Microvascular Endothelial Cells (HUtMEC) are isolated from the myometrium (middle layer of the uterine wall) from single donors who are not pre-treated with hormones. The cells stain positive for CD31 and von Willebrand factor and negative for smooth muscle α-actin.

During pregnancy HUtMEC propagate intensely and change their phenotype and expression pattern in response to sex steroids. This includes up-regulation of HUtMEC nitric oxide synthase activity, modulation of adhesion molecule expression, and an increase in endothelial cell survival and angiogenic activity. HUtMEC are involved in medical conditions like uterine fibroma or adenomysis.

Recommended plating density 10000 - 20000 cells per cm2
Passage after thawing P2
Tested markers CD31 positive, Dil-Ac-LDL uptake positive
Guaranteed population doubling > 15

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