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Human Dermal Lymphatic Endothelial Cells (HDLEC)
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Primary Human Dermal Lymphatic Endothelial Cells isolated from different sources (e.g. juvenile foreskin). CD31 positive, Podoplanin positive.

Unit 500000 cells
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Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.

Human Dermal Blood Endothelial Cells (HDBEC) from the same donor are available on request.

Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.

Recommended plating density 10000 - 20000 cells per cm2
Passage after thawing P2
Tested markers Podoplanin positive, CD31 positive
Guaranteed population doubling > 15
Image
Figure 1.Exemplary flow cytometric analyis of our HDLEC. 99% of the cells are CD31 positive.
Image
Figure 2.Exemplary flow cytometric analysis of our HDLEC. 96% of the cells are podoplanin positive.

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